标题: Pharmaceutical and Environmental Chemicals [打印本页] 作者: ipgood 时间: 2007-12-20 12:04 标题: Pharmaceutical and Environmental Chemicals Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals
Publisher: Wiley-Interscience
Number Of Pages: 814
Publication Date: 2007-06-29
Sales Rank: 1075736
ISBN / ASIN: 0470049626
EAN: 9780470049624
Binding: Hardcover
Manufacturer: Wiley-Interscience
Studio: Wiley-Interscience
A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals
This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins. It covers the in vitro models used, newer technologies, and regulatory aspects. The book offers a complete systems perspective to risk assessment prediction, discussing experimental and computational approaches in detail, with:
An introduction to toxicology methods and an explanation of computational methods
In-depth reviews of QSAR methods applied to enzymes, transporters, nuclear receptors, and ion channels
Sections on applying computers to toxicology assessment in the pharmaceutical industry and in the environmental arena
Chapters written by leading international experts
Figures that illustrate computational models and references for further information
This is a key resource for toxicologists and scientists in the pharmaceutical industry and environmental sciences as well as researchers involved in ADMET, drug discovery, and technology and software development作者: ipgood 时间: 2007-12-20 16:44
Pharmaceutical and Environmental Chemicals作者: cygyc-gc 时间: 2007-12-20 16:46
全英文的，看起来太困难了作者: wzqings 时间: 2008-2-10 19:22
下了，感谢提供！ip你的qq是多少，这样的人才真是太少见了作者: howwelldl 时间: 2008-2-19 21:35
文章好,书好,花点钱值得!不过能少还是少点作者: yimeng 时间: 2009-8-3 15:04
就是不错的资料 先收藏了 呵呵作者: garfield_mzl 时间: 2012-4-28 17:38
楼主提供的资料很有用，下载收藏了，谢谢！
